The Simpsons bosses say they’d love the Duke and Duchess of Sussex to make a cameo on the show.
While they say they haven’t approached former actress Meghan directly, they say they’d be very happy to hear from her.
Last year Prince Harry was caught on camera touting his wife for a voice over job to Disney chairman Robert Iger at the Lion King premiere.
Actress Yeardley Smith, who plays Lisa Simpson, also said she’d love Greta Thunberg to appear on the long-running cartoon.
The brainiest of the Simpson clan, Lisa long been an environmental campaigner and vegetarian – just like her idol Thunburg.
Smith, who has voiced Lisa since her creation in 1987, said: “It’d be great if Greta plays herself – she’d be passing through Springfield and find that she has so much in common with Lisa.
“But the heart breaker would be when Greta moved on to her next stop and Lisa would be with all those people in the town who wish she’d just keep her trap shut. She’d have to carry the torch for the rest of time on her own.”
The long-running cartoon has a history of high-profile cameos, which have included The Red Hot Chilli Peppers, former Beatle Ringo Starr and Johnny Cash.
An episode of the show featuring the voice of Michael Jackson (titled Stark Raving Dad) was pulled from air following allegations of child sexual abuse against the late singer.
Producers have also admitted they would rethink the voice casting of the role of Indian store owner Apu if they were starting the 30-year-old show all over again.
American actor Hank Azaria says he will no longer voice the character of Apu following years of controversy and accusations of racism.